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U-47700 research chemical properties
CAS No.: 121348-98-9
Appearance: white powder
Formula Name: C16H22Cl2N2O
Molecular weight:329.265 g/mol
More information about U-47700 research chemical
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U-47700 gets the systematic and formal IUPAC name 3,4-Dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide. It provides a molar mass of 329.27 grams plus an empirical chemical formula of C16H22Cl2N2O. U47700 is part of the drug class opioid analgesics. Particularly U47700 is among the benzamide kind of opioids. It isn’t used medically but within research.
In animal models U47700 was shown to possess potency 7.5 occasions greater than the classical medicinal opiate morphine. It had been initially created by several researchers within the pharmaceutical firm Upjohn in four decades ago. This compound is not fit for human or animal consumption. U47700 can be a structural analogue from the earlier opioid AH-7921.
Pharmacologically U47700 can be a selective agonist within the ì-opioid receptor getting a Kd of 5.3 nM instead of a considerably weakened binding interaction within the kappa opioid receptor where U47700 have a very Kd price of 910 nM. Online reports although subjective and unverifiable do indicate numerous characteristics from the chemical substance substance.
U47700 is reported to produce feelings of pleasure, discomfort relief and suppression of hysteria. A number of users have reported effects like the broadly mistreated pharmaceutical oxycodone. Excitement is reported as lower when compared with morphine or heroin. The sensation produced is called feelings of °warmth ± and °comfort ± which matches using your body. U47700 is reported as causing significantly greater sedation than comparable opiates like oxycodone or hydrocodone.
Other effects include home loan business libido, constriction in the pupils, difficulty urinating, suppression of cough and constipation. This can be in conjuction with the overall unwanted effects of opiates. U47700 could cause increase the risk for skin feel completely itchy due to relieve histamine.
Respiratory system system depression can be a serious side-aftereffect of numerous opioids and makes up about the lethality of individuals compounds. Despite there being no formal studies towards the physiological action of U47700 in humans anecdotal reports indicate a inclination of U47700 to produce a lot more effective respiratory system system depression than heroin or morphine. This makes U47700 a dangerous compound and users need to approach with careful attention. At low doses it’s reported that U47700 slows the breath moderately and may not produce a very noticeable impairment.
Greater doses and overdoses overpower the customer with abnormal breathing patterns reported, breathlessness and lack of knowledge. This might quickly lead to fatal brain damage. U47700 like other opioids does produce numerous undesirable effects that are in modern language known as crash . Incorporated within this are agitation, irritability, negative emotional states, cognitive fatigue, difficulty thinking, anxiety, depression and inadequate motivation.
U47700 features a marked toxicity in compliance with dose due to its extreme potency when compared with traditional opioids and opiates. This makes it a under ideal recreational compound with significant possibility of injuries towards the consumer. Therefore caution needs to be labored out regarding dose. Lethality in the compound may also be exacerbated by concurrent usage of other depressants for instance alcohol, benzodiazipines, GHB/GBL and dissociatives for instance ketamine.